Genome / Genetics

Profilbild Professorin Kaufmann
Faculty of Life Sciences
Department of Biology

Plant cell and molecular biology

Share Profile Link
Profile link copied.
Profil Link teilen
Profil Link wurde kopiert.
Expertise

Prof. Kaufmann's research and that of her research group is concerned with the molecular mechanisms of gene regulation in plants. Plant developmental processes require coordinated changes in the activity of a large number of genes in the nucleus. These are controlled by specific transcription factors interacting with epigenetic regulators. We are investigating the molecular modes of action and gene regulatory networks of these regulatory proteins.

In addition, Kaufmann and her team are interested in environment-independent variation, and evolutionary changes in these networks. In addition, there is interest in the molecular mechanisms that control the activities of genes during development, using a combination of epigenomics, proteomics, and classical genetics. Their model system is flower development. By combining experimental and computational analyses, the team aims to understand multicellular development at the systems level.

Scientific Services
  • molecular biological, biochemical and genetic approaches e.g. ChIP-seq, SELEX-seq, protein complex isolation, gene expression studies and classical genetics
MEHR ANZEIGEN
Profilbild Prfessorin Greven
Faculty of Economics and Business Administration

Chair of Statistics

Share Profile Link
Profile link copied.
Profil Link teilen
Profil Link wurde kopiert.
Expertise

Professor Greven's expertise is particularly in statistics, data science, statistical learning, machine learning, statistical modeling, statistical inference, biostatistics, and their applications in various fields (economics, social sciences, medicine, epidemiology, engineering, linguistics, etc.). She is also well-versed in functional data analysis and statistics for object data (curves, images, shapes, etc.).

  • 2 projects on functional data analysis for sensor data with Siemens CT
MEHR ANZEIGEN
Profilbild Winter
Faculty of Life Sciences
Department of Biology

Cognitive Neurobiology

Share Profile Link
Profile link copied.
Profil Link teilen
Profil Link wurde kopiert.
Expertise

Prof. Winter’s research is focused on animal behaviour, especially cognitive performance, e.g. learning ability, memory and their neurobiological foundation for foraging. He carries out behavioural assessments for mice and rats, mostly for preclinical research, to investigate decision-making processes in animals. Lab space is available, inter alia at the Berlin Mouse Clinic for Neurology and Psychiatry (BMC), one of the leading diagnostic institutions within the NeuroCure Cluster of Excellence. Prof. Winter and his team also advise on experimental design and develop automated equipment and systems for behavioural studies on rodents for external laboratories. Another area of his expertise is virtual reality for humans. Here Prof. Winter focuses on the development of a compact, mobile, and immersive virtual reality environment for a wide range of uses.

Scientific Services

Behavioural analysis:

  • Computer controlled sensor and actuator systems for manipulation and measuring of behaviour
  • Modular software system for automated measuring of behaviour
  • RFID technology

Virtual reality:

  • Immersive 3D-virtual reality system with closed monitoring (octagon)
  • Software for rapid implementation of specific VR-applications and interaction scenarios
  • Planning and development of a system for automated diagnostics of parameters for motor skills after clinical surgery for a large international pharmaceutical group. 24h recording and measurement as operator independent system.
MEHR ANZEIGEN
Profilbild Leser
Faculty of Mathematics and Natural Sciences
Department of Computer Science

Knowledge Management in Bioinformatics

Share Profile Link
Profile link copied.
Profil Link teilen
Profil Link wurde kopiert.
Company testimonials

IT system house
IT product manufacturer
international pharmaceutical company
medium-sized biotechnology company

Expertise

The research of Prof. Leser and his group is focused on all aspects of management, integration and analysis of heterogeneous, large and distributed data sets including natural language texts (text-mining and information extraction). This encompasses subjects such as data warehouses and ETL, graph databases, deep web and semantic web, machine learning, similarity search, scientific workflows, statistical methods of data analysis as well as methods for assessing and securing data quality. The team of Professor Leser conducts research in a variety of interdisciplinary projects, especially with colleagues from the life sciences covering the range from basic molecular biology to Systems Medicine.

http://humboldt.gmbh/forschungskooperation

Scientific Services

Very good IT-facilities:

  • several state-of-the-art parallel computer cluster (20-80 CPUs, 1 TB main memory)
  • cluster with 60+ cores
  • 50TB+ storage
  • For an IT service provider: Consultancy  and prototype development in the field of master data standardisation and integration
  • For an IT-manufacturer: Development and valuation of algorithms for analysing data quality
  • For an international pharmaceutical company: Consultancy and development of text-mining-procedures in biomarker development
  • For a medium-sized biotech company: Joint system development (partly funded by the German Federal Ministry for Economic Affairs and Energy) in the field of human genotype changes evaluation
MEHR ANZEIGEN