Healthcare & Life Sciences

Prof. Nadja Klein
Faculty of Economics and Business Administration

Emmy Noether Research Group in Statistics and Data Science

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Expertise

Professor Klein is an expert in statistics, and her research has been successfully used in many interdisciplinary applications, including the fields of medicine, ecology, life sciences, and economics. 

Her research interests cover those on Bayesian Computational Methods and Bayesian Deep Learning, which allow for uncertainty quantification and better interpretability in several model classes, but are also scalable to large data sets and highly-parameterized models.

Beyond that Prof. Klein also works in distributional regression models, which are particularly useful in analysing complete distributions of quantities of interest in the presence of complex associations with influential variables. These models also allow to model dynamics in space and time, thus relating her research to spatial statistics.

Furthermore, Prof. Klein works on general smoothing and shrinkage methods in the context of statistical and machine learning as well as on network analysis.

 

  • Newsenselab: Transferbonus for analyses of migraine data
  • Zalando: Master thesis on Bayesian models in e-commerce
  • Deutsche Kreditbank AG
  • Lufthansa Technik AG
  • since 2021:  Experiment (Volkswagenstiftung)
  • 2019–2020: Transferbonus with Newsenselab (Humboldt Innovation GmbH)
  • since 2019:  Emmy Noether Research Group
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Profilbild Nuissl
Faculty of Mathematics and Natural Sciences
Department of Geography

Applied geography and spatial planning

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Expertise

Prof. Nuissl is concerned with the development of cities and regions. He investigates the growth of cities and settlement areas, dynamics on the housing market (esp. displacement processes) as well as the development of city districts and neighborhoods. In addition, one focus of his work is the analysis of municipal planning and policy processes. As a member of the Integrative Research Institute on Transformations of Human-Environment Systems (IRI THESys), Prof. Nuissl has excellent interdisciplinary connections in his field of research.

Scientific Services
  • Contract research (qualitative and quantitative social science methods)
  • Expert reports
  • City of Munich: Case Study on Displacement Processes in the Housing Market and Derivation of Urban Policy Implications (https://www.muenchen.de/rathaus/Stadtverwaltung/Referat-fuer-Stadtplanu…)

  • vhw Bundesverband für Wohnen und Stadtentwicklung (Federal Association for Housing and Urban Development): Study on the change of local political cultures in a polarized society

  • FGW - Forschungsinstitut für die gesellschaftliche Weiterentwicklung (North Rhine-Westphalia): Study on the integration of migrants in the neighborhood (https://www.fgw-nrw.de/forschungsergebnisse/forschungsergebnisse/projek…)

  • CBRE: Data collection on student housing in Germany

  • IRI THESys - Integrative Research Institute on Transformations of Human-Environment Systems at the Humboldt University of Berlin

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Prof. Danilov
Faculty of Economics and Business Administration

Management

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Expertise

Professor Danilov is engaged in empirical human resource management research, as well as the identification of causal relationships of the effect of human resource management tools on employee motivation and productivity. She also conducts research in organizational and human resource economics, in the field of empirical human resource management (HRM), and in the course of this she works with Big Data and People Analytics using machine learning.

 

Scientific Services
  • randomized studies (A/B tests) on incentive setting
  • work design and employee motivation
  • analysis of data (accounting, personnel, etc.)
  • "Delegation of decision making and productivity and employee satisfaction" at a world-leading energy company.
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Profilbild Hillmann
Faculty of Life Sciences
Albrecht Daniel Thaer-Institute of Agricultural and Horticultural Sciences

Animal husbandry systems and ethology

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Expertise

Professor Hillman's research focuses on the influence of husbandry conditions and management practices on the welfare of farm animals. Her research in the area of animal welfare ranges from the validation of animal welfare indicators, including animal health, to the practical implementation of animal welfare measures.

Hillmann and her team concentrate on animal behavior. In addition, they use information on animal health, such as (stress)-physiological variables and economically relevant characteristics (e.g., meat quality).

Ethical and legal considerations also play a role in her research. However, practical problems in animal husbandry are in the foreground.  Besides classical behavioral observations, often with the help of video recordings, stress-physiological, clinical and cognitive parameters are added, but also techniques for automated recording of animal behavior.
Many problems in animal husbandry are related to a disturbance in behavioral control. Professor Hillmann's basic research in behavioral control thus also leads to solutions of practically relevant behavioral problems in farm, pet, laboratory, and zoo animals. Such solutions work at the roots of the problems because they are based on causal understanding of the underlying control mechanism.
In both application and basic questions, the measurement and consideration of the animals emotion plays a critical role as a component in the control of behavior, as well as in relation to their welfare.

Her research thus moves in the area of tension between scientific/clinical basic research, application and questions from the fields of agricultural economics and social sciences.

Scientific Services
  • Equipment for behavioral observation (video/3D acceleration)
  • NaTiMon (BMEL): Development of basic principles for regular, indicator-based monitoring and reporting on the status of animal welfare of sheep and goats in Germany, as well as its change over time. This animal welfare monitoring is intended to take into account the various dimensions of animal welfare at the relevant stages of the animals' lives (husbandry, slaughter, transport)

  • PanSens ( Agricultural Pension Bank): The object of the sub-project is the application of the reference system for standing and lying times, the basic validation of the parameters movement activity and standing and lying times, and the scientific monitoring of the development work and the iteration for the detection of specific cow diseases. Practice partner: dropnostix GmbH

     

  • Education and training for animal experimenters (selective)
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Profilbild Professor Akbik
Faculty of Mathematics and Natural Sciences
Department of Computer Science

Chair of Machine Learning

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Expertise

Prof. Dr. Alan Akbik conducts research in the field of machine learning (ML) and natural language processing (NLP). His goal is to enable machines to capture, understand, and use natural language like a human.

To this end, he has developed one of the world's leading deep learning frameworks for NLP, which is already being used in over 1,000 research and industrial projects.

https://indd.adobe.com/view/d0350ae0-6591-4f69-ad02-6d2508979a8f

Scientific Services

Consulting in:

  • Deep Learning
  • Natural Language Processing (NLP)
  • Machine Learning (ML)
  • 3 Patents at IBM Research
  • Zalando Outstanding Achievement Award
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Enrico Klotzsch
Faculty of Life Sciences
Department of Biology

Biophysics and Mechanobiology

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Topics / Trends
Expertise

Professor Klotzsch research is focussed on the field of materials science for optiminzing adaptive immuntherapies. Furthermore he is engaged in the immun systems mechanbiology. 

He and his team aim to bridge the gap between structural and cell biology, and in particular to unravel the mechanistic aspects of how cells sense and respond to their environment.  This includes how cells use forces to study interactions with other molecules such as receptor-ligand interactions to switch biochemical functions, such as T-cell activation, migration, or their interaction with the extracellular matrix. We are also investigating how these findings can be used for biomedical applications.

We use state-of-the-art single molecule microscopy techniques such as super-resolution microscopy, AFM and optical tweezers to gain insights into general aspects of mechanobiology, membrane biophysics, neurobiology and immunology.

Scientific Services
  • Super-Resolution Mikroscopy
  • transcriptomics
  • mechanical tests with biological materials
  • T-cells activation
  • characterization of lymphocytes
  •  comparative studies of products for CAR T cell therapy
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Profilbild Winter
Faculty of Life Sciences
Department of Biology

Cognitive Neurobiology

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Expertise

Prof. Winter’s research is focused on animal behaviour, especially cognitive performance, e.g. learning ability, memory and their neurobiological foundation for foraging. He carries out behavioural assessments for mice and rats, mostly for preclinical research, to investigate decision-making processes in animals. Lab space is available, inter alia at the Berlin Mouse Clinic for Neurology and Psychiatry (BMC), one of the leading diagnostic institutions within the NeuroCure Cluster of Excellence. Prof. Winter and his team also advise on experimental design and develop automated equipment and systems for behavioural studies on rodents for external laboratories. Another area of his expertise is virtual reality for humans. Here Prof. Winter focuses on the development of a compact, mobile, and immersive virtual reality environment for a wide range of uses.

Scientific Services

Behavioural analysis:

  • Computer controlled sensor and actuator systems for manipulation and measuring of behaviour
  • Modular software system for automated measuring of behaviour
  • RFID technology

Virtual reality:

  • Immersive 3D-virtual reality system with closed monitoring (octagon)
  • Software for rapid implementation of specific VR-applications and interaction scenarios
  • Planning and development of a system for automated diagnostics of parameters for motor skills after clinical surgery for a large international pharmaceutical group. 24h recording and measurement as operator independent system.
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Profilbild Weidlich
Faculty of Mathematics and Natural Sciences
Department of Computer Science

Process-Driven Architectures

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Expertise

Prof. Weidlich is a professor at the Department of Computer Science, where he leads the Process-Driven Architectures research group. The goal of his team is to support and improve the design and the analysis of process-oriented information systems (POIS) and event-driven systems (ES). POIS are software systems that help to automate, monitor, and control processes. These systems are established in various domains, from logistics, through healthcare, to infrastructure monitoring. The team’s research focuses on formal methods for behavioural modelling and verification, event-driven approaches to monitor and control processes, as well as questions related to process-driven data integration. The group further works on techniques that optimise the run-time behaviour of event-driven systems. In particular, the evaluation of event queries over streams can be designed more efficiently once regularities within event streams have been detected. In 2016, Prof. Weidlich was named Junior Fellow of the German Informatics Society (Gesellschaft für Informatik, GI) and awarded with the Berlin Research Prize (Young Scientist) by the Governing Mayor of Berlin.

Scientific Services
  • extensive experience with the documentation of business processes and in training for process management techniques
  • expertise in process mining, data-driven analysis of processes in terms of qualitative (compliance requirements) and quantitative (bottleneck-analysis, management of resource deployment) properties
  • know-how in scalable infrastructures for event stream processing
  • for a leading US cancer clinic: analysis and improvement of clinical processes based on the data of a real-time-locating-system
  • for an international oil and gas group: development of techniques for detecting irregularities in streams of sensor data
  • for a well-known German manufacturer of enterprise software: design and development of add-ons for a business process modelling platform
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Profilbild Völkle
Faculty of Life Sciences
Department of Psychology

Multivariate research methods

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Expertise

Professor Voelkle is an expert in Quantitative Psychology. He and his team work on the development and adaptation of new assessment procedures, the statistical and mathematical modeling of psychological processes, the design of studies as well as the analysis and interpretation of empirical-psychological data. Special emphasis of the research conducted at professor Voelkle’s lab lies on the analysis of longitudinal data and evaluation research. Professor Voelkle and his team are often involved as consultants in research and development projects in the education and health sector. To improve applied empirical research in the social and life sciences, they have founded the Berlin Methods Group in 2017.

Scientific Services

Powerful computers and access to all common statistical programs

  • Health: Evaluation and statistical advice for psychological-medical research facilities and health insurance companies
  • Education: Evaluation and statistical consulting for private and public project executing organisations
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Profilbild Ulrichs
Faculty of Life Sciences
Albrecht Daniel Thaer-Institute of Agricultural and Horticultural Sciences

Department of Crop and Animal Sciences, Urban Ecophysiology of Plants

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Expertise

Prof. Ulrichs is an expert in the field of ecophysiology of plants with a special focus on plants in urban spaces. His team studies processes, which determine plant growth, e.g. stress exposure in an urban environment. The emphasis of his research lies on the analysis of the secondary metabolite balance (incl. its nutritional function), substance allocation, competition and plant-insect interaction. Prof. Ulrichs other major field of expertise is the quality assurance in food supply chains of horticultural products, especially for perishable foodstuffs like fruits and vegetables in temperate zones as well as in tropical/subtropical regions.

Scientific Services
  • molecular methods
  • in-vitro propagation
  • HPLC
  • GC/MS
  • electroantennogram studies
  • trace gas analysis using photoacoustic spectroscopy
  • German specialty chemicals group: development of nanostructured plant protection agents
  • H. Lorberg Baumschulerzeugnisse GmbH & Co. KG (tree nursery): selection of climate-tolerant boulevard trees (Alleebaum)
  • Bein GmbH: development of electrostatic application processes of nanostructured elements
  • Bayer Crop Science: biosensors to prove the existence of plant viruses
  • XEROFLOR: development of vegetation carriers to prevent soil erosion in the Alps
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Profilbild Leser
Faculty of Mathematics and Natural Sciences
Department of Computer Science

Knowledge Management in Bioinformatics

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Expertise

The research of Prof. Leser and his group is focused on all aspects of management, integration and analysis of heterogeneous, large and distributed data sets including natural language texts (text-mining and information extraction). This encompasses subjects such as data warehouses and ETL, graph databases, deep web and semantic web, machine learning, similarity search, scientific workflows, statistical methods of data analysis as well as methods for assessing and securing data quality. The team of Professor Leser conducts research in a variety of interdisciplinary projects, especially with colleagues from the life sciences covering the range from basic molecular biology to Systems Medicine.

https://indd.adobe.com/view/d0350ae0-6591-4f69-ad02-6d2508979a8f

Scientific Services

Very good IT-facilities:

  • several state-of-the-art parallel computer cluster (20-80 CPUs, 1 TB main memory)
  • cluster with 60+ cores
  • 50TB+ storage
  • For an IT service provider: Consultancy  and prototype development in the field of master data standardisation and integration
  • For an IT-manufacturer: Development and valuation of algorithms for analysing data quality
  • For an international pharmaceutical company: Consultancy and development of text-mining-procedures in biomarker development
  • For a medium-sized biotech company: Joint system development (partly funded by the German Federal Ministry for Economic Affairs and Energy) in the field of human genotype changes evaluation
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Profilbild Legerlotz
Faculty of Humanities and Social Sciences
Department of Sports Sciences

Department of Training and Movement Sciences

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Company testimonials

Olympic Centre Berlin (Olympiastützpunkt Berlin)

Expertise

Professor Legerlotz is head of the Movement Biomechanics research group in the Department of Training and Movement Sciences. The research team focuses on different aspects of tendon adaptation. This includes the adaptation of connective tissues to strain in general and also the emergence, rehabilitation and prevention of tendon injuries in particular. Current research analyses the effect of changing hormone levels on the mechanical properties of the female tendon and training interventions that are used to treat athletes with tendinopathy.

Scientific Services

The departments offers three large laboratories with modern sports science equipment:

  • Motion Analysis Laboratory with a VICON system including twelve cameras and three AMTI force plates. Both the foundations of the force platforms as well as the camera mounts are decoupled from the sports ground of the laboratory to prevent the transmission of vibrations.
  • Force Diagnostic Laboratory with DAVID and Technogym strength diagnostics equipment for all major muscle groups
  • EMG laboratory with a Biodex System-3 and an Esaote ultrasound machine, which is used to study the muscle-tendon plasticity. To control the joint angle at the Biodex camera, mounts are available for installing eight VICON cameras. A large LCD-Screen provides the possibility for biofeedback.

All labs are air-conditioned and are equipped with an uninterruptible power supply and complete darkening.

Various projects with Olympic Centre Berlin (Olympiastützpunkt Berlin), from training adaptation to injury prophylaxis

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Prof. Hoppe
Faculty of Life Sciences
Department of Psychology

Occupational Health Psychology

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Expertise

Prof. Hoppe’s research is focused on Occupational Health Psychology (OHP) especially on the analysis of work activities to maintain employee health and performance as well as to provide learning and development opportunities. OHP integrates occupational and health psychology with occupational medicine and traditional labor safety, which is insufficient for today’s flexible employment situation. Prof. Hoppe also examines the psychosocial characteristics of a specific workplace, e.g. work requirements or the level of influence on and control over tasks as well as the social working environment. She also studies the effects of these characteristics on employee health and his/her well-being. She investigates how psychosocial work characteristics influence an employee’s motivating factors like job satisfaction and commitment. Particular attention is paid to the situation of migrant and low-skilled workers and the analysis of the impact their workplaces and work environments may have on their health and well-being. Moreover, Prof. Hoppe studies multi-ethnic and -lingual workforces and the effects of diversity on employee health.

Scientific Services
  • risk assessment methods for workplace conditions
  • employee surveys regarding the promotion of health at workplace
  • postal operators, logistics companies, professional care providers, manufacturing companies: execution of employee surveys to gather data on psychosocial strain and resources in the workplace and to analyse effects of stress, job satisfaction and work performance
  • public institutions (e.g. universities, federal ministries), consulting companies, self-employed persons: development of health-related interventions and training sessions via mobile devices (e.g. smartphones, tablets) to facilitate recovery strategies and self-management
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Profilbild Grimm
Faculty of Life Sciences
Department of Biology

Plant Physiology

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Expertise

Prof. Grimm and his team mainly investigate the metabolic control of tetrapyrrole biosynthesis and photosynthesis. They also do research on the regulation of sucrose transport in plants. The plant science team is interested in studying the unique properties and functions of plant cells, such as intracellular communication between the nucleus and the two main plant organelles, plastids and mitochondria. Prof. Grimm’s group applies several experimental methods and techniques from the areas of biochemistry, genetics, molecular and cell biology in their research and in the training programs for students and young academics.

Scientific Services

The Plant Physiology group provides all necessary equipment and instrumentation for plant growth and molecular genetics, biochemical and physiological work:

  • S1 greenhouse
  • growth cabinets for Arabidopsis
  • radionuclide laboratory
  • HPLC equipped with diode array and fluorescence detector
  • FPLC
  • fluorescence spectrometer
  • microtiter plate reader (w/ fluorescence detection)
  • UV/Vis photometer • PAM-2000 fluorometer
  • LI-COR photosynthesis device
  • fluorescence microscope
  • ultracentrifuges and high speed centrifuges including rotors
  • clean benches
  • incubators for growth of genetically modified bacteria and yeast
  • several PCR machines, e.g. microplate readers and PCR light cycler
  • confocal laser scanning microscope (CLSM)
  • Oil mills: pigments in rapeseed oil
  • Food-producing corporation: postharvesting treatment and storage of leafy greens
  • Pharmaceutical group: vitamin synthesis and content in plants
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Profilbild Eisert
Faculty of Mathematics and Natural Sciences
Department of Computer Science

Visual Computing

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Expertise

The chair of Visual Computing develops new methods for the analysis and synthesis of image and video data. This includes algorithms for estimating shape, material, motion and deformation from monocular and multi-view camera systems. Both in national and international collaborations, those algorithms are exploited in applications like multimedia, VR/AR, industry, medicine, and security.

Scientific Services
  • Various cameras
  • Multispectral sensors, 3D sensors
  • Lighting and calibration systems
  • Development of new methods for automatic inspection and damage classification of sewer networks with a water supply company
  • Development of augmented reality systems for automobile production processes with a car manufacturer
  • Analysis of multispectral imaging for tissue classification in collaboration with medical technology manufacturer
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Profilbild Dobbek
Faculty of Life Sciences
Department of Biology

Structural Biology / Biochemistry

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Expertise

Prof. Dobbek analyses the biochemical principles of bacterial growth on substrates, i.e. carbon dioxide, carbon monoxide as well as aromatic compounds, which also are pollutants. The main focus lies on the functional and structural investigation of metalliferous enzymes that transform unreactive molecules in oxygen free conditions and thus enable bacteria to grow in a seemingly hostile environment. Developing new (biological) catalysts capable of energy-efficiently transforming carbon dioxide and monoxide is Prof. Dobbek’s goal. Moreover these catalysts are designed to generate new enzymes for the biological decomposition of substances damaging to humans and the environment.

Scientific Services
  • production of proteins under aerobic and anaerobic conditions (FPLC and HPLC procedures)
  • robotic protein crystallization under standard conditions and in oxygen free conditions (glovebox technique)
  • crystallographic structural analysis of proteins
  • general methods in the field of structural bioinformatics
  • methods to examine enzymatic processes, e.g. fast mixing methods (stopped-flow spectroscopy under aerobic and anaerobic conditions), analyses using HPLC, GC-MS, UV/Vis- and fluorescence spectroscopy, isothermal titration calorimetry under aerobic conditions
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Profilbild Arampatzis
Faculty of Humanities and Social Sciences
Department of Sports Sciences

Trainings and Movement Sciences

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Company testimonials

zebris Medical GmbH, myon AG, Simi Reality Motion Systems GmbH

Expertise

Prof. Arampatzis and his Department of Training and Movement Sciences are dealing with the interaction of the neural and musculoskeletal system in research and teaching. Of special interest for Prof. Arampatzis is the adaptation of the neural and musculoskeletal system by mechanical stress and its influence on human performance as well as motor control and motion security. Through an integrative approach of biomechanics, physiology and neuroscience, consequences for athletes and for people with degenerative changes of the neural and musculosceletal systems will be deduced. The main research focus of the department is on quantifying and changing the neuro-biomechanical potential of humans and on the investigation of its influence on the mobility in everyday life and sports. Considering this, the department also investigates the role of sports activities in order to prevent accidents and to preserve the quality of life for the elderly and people with chronic diseases.

Scientific Services

The departments offers three large laboratories with modern sports science equipment:

  • Motion Analysis Laboratory with a VICON system including twelve cameras and three AMTI force plates. Both the foundations of the force platforms as well as the camera mounts are decoupled from the sports ground of the laboratory to prevent the transmission of vibrations.
  • Force Diagnostic Laboratory with DAVID and Technogym strength diagnostics equipment for all major muscle groups
  • EMG laboratory with a Biodex System-3 and an Esaote ultrasound machine, which is used to study the muscle-tendon plasticity. To control the joint angle at the Biodex camera, mounts are available for installing eight VICON cameras. A large LCD-Screen provides the possibility for biofeedback. All labs are air-conditioned and are equipped with an uninterruptible power supply and complete darkening.
  • zebris Medical GmbH: evaluation of pressure distribution measurements in treadmills
  • myon AG: evaluation of a wireless electromyography system aiming to quantify muscle activation
  • Simi Reality Motion Systems GmbH: evaluation of a 3D motion capture system designed to analyse complex human movements
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